BRCA1 Collection

This collection of chemical and molecular structures has been assembled to complement the Bio-ITEST Genetic Testing curriculum strand. All the structures below can be viewed in Molecule World on the iPad or Molecule World for iPhone.   ****Includes NEW structures!****


Structures in the collection

Type Description Download structure
An MW Collection

To view this collection of BRCA1 structures, you will need to download and install the iPad version of Molecule World.  Once Molecule World is installed on your iPad, return to this page and download the entire collection at once by selecting the mwc file.  

Binary Data brca1.mwc
PDB

BRCA1 carboxyl terminal end with BRCT repeats, bound to CtIP phosphopeptide, a partner in detecting and repairing DNA.

MMDB

BRCA1 carboxyl terminal end, contains BRCT repeats and the CtIP binding domain.  M1775

MMDB

BRCA1 carboxyl terminal end, BRCT repeats.  Contains the CtIP binding domain and M1775r mutation.

PDB

BRCA1 carboxyl terminal end, BRCT repeats.  Contains the CtIP binding domain and M1775k mutation.

PDB

BRCA1 carboxyl terminal end with BRCT repeats, bound to CtIP phosphopeptide, a partner in detecting and repairing DNA. Contains the normal amino acid G1656.

PDB

BRCA1 carboxyl terminal end, BRCT repeats. Modeling was used to align 3PXA to 1Y98 and add the CtIP phosphopeptide. Contains the G1656d missense mutation.

PDB

BRCA1 carboxyl terminal end with BRCT repeats, bound to CtIP phosphopeptide, a partner in detecting and repairing DNA. Contains the normal amino acid R1699.

PDB

BRCA1 carboxyl terminal end with BRCT repeats. Modeling was used to align 3PXC to 1Y98 and add the CtIP phosphopeptide. Contains the R1699q missense mutation.

PDB

BRCA1 carboxyl terminal end with BRCT repeats, bound to CtIP phosphopeptide, a partner in detecting and repairing DNA. Contains the normal amino acid T1700.

PDB

BRCA1 carboxyl terminal end with BRCT repeats.   Modeling was used to align 3PXB to 1Y98 and add the CtIP phosphopeptide.  Contains the T1700a missense mutation.

PDB

BRCA1 carboxyl terminal end with BRCT repeats, bound to CtIP phosphopeptide, a partner in detecting and repairing DNA. Contains the normal amino acid V1809.

PDB

BRCA1 carboxyl terminal end with BRCT repeats.   Modeling was used to align 1T2U to 1Y98 and add the CtIP phosphopeptide. Contains the V1809f missense mutation.

PDB

BRCA1 carboxyl terminal end with BRCT repeats, bound to CtIP phosphopeptide, a partner in detecting and repairing DNA. Contains the normal amino acid D1840.

PDB

BRCA1 carboxyl terminal end with BRCT repeats.   Modeling was used to align 3K16 to 1Y98 and add the CtIP phosphopeptide. Contains the D1840t missense mutation.

MMDB

A short chain of double-stranded DNA showing hydrogens. Hydrogens are present because this structure was solved by NMR.