Genomics

Cofactor Genomics is offering to sequence a genome for a few classes for free using Next Generation DNA Sequencing technology (either Illumina GA or via AB SOLiD). Quoting from their site:
Cofactor will ask course organizers for a 1 page description of how their ~700Mb sequencing project could be used as an effective teaching aid in their class. We will review and choose the best entries during the month of May. Those entries will be awarded a free sequencing project ... Read more

"Digital biology," as I use the phrase, refers to the idea of using digital information for doing biology. This digital information comes from multiple sources such as DNA sequences, protein sequences, DNA hybridization, molecular structures, analytical chemistry, biomarkers, images, GIS, and more. We obtain this information either from experiments or from a wide variety of databases and we work with this information using several kinds of bioinformatics tools.

The reason I'm calling this field "digital biology" and not "bioinformatics" (even though I typically use the terms ... Read more

The New York Times had a great article a couple of days ago on the need for personalized medicine to become more than a catchy phrase. As we're learning more about the interaction between genes and drug metabolism, we're also learning that large numbers of people are either taking the wrong drug or taking drugs that won't work.

tags: ,

Researchers have known for some time that genetic variants determine how well drugs work. Some versions of a gene cause a drug to be metabolized faster, some slower, and when combined, at an ... Read more
Genome Web's Daily Scan noted an interesting blog post today from John D. Halamka, one of the people to get his genome sequenced through the personal genome project. I was interested to see his post since Genome Web wrote that he was discussing data standards and we have been writing quite a bit, ourselves, about data measurements for Next Gen sequencing (e.g. Next Gen-Omics) on our company blog, ... Read more
Masha Gessen was faced with a terrifying choice: cut off her breasts, and possibly save herself from cancer, or use them to feed her child. It was late at night when I walked back to my empty dorm room at the conference. Shivering, I stood on the narrow bed, quickly shut the windows, tore the blankets off the other bed, and wrapped myself up, trying to get warm. Too cold to sleep, I picked up my copy of Masha Gessen's " ... Read more
Maybe you did it for the extra cash. Maybe you wanted to be part of the sperm cube public art project. Whatever the reason, it's possible, just possible, your sperm took on a life of it's own, once you left it. And now that a genome is no longer an entirely personal bit of information, you may be in for a surprise meeting someday, with the end result. That's right. Male adoptees are getting their DNA tested and getting information about their possible surnames. According to ... Read more
Last week, while attending the ISB "DNA of Innovation" symposium in honor of Lee Hood's 70th birthday, I decided to try live-blogging for the first time. Unbeknownst to others in the audience, except my husband, I quietly typed away, collecting notes and uploading impressions. But battery power has its limits, even when I have more notes to share. And despite all the fascinating speakers, I have notes enough to describe just one more. The personal genome days have only just begun, but George Church is already looking into the future. In a true "Lee Hood style tour de force ... Read more
Let's play anomaly! Most of this week, I've written about the fun time I had playing around with NCBI's Blink database and finding evidence that at least one mosquito, Aedes aegypti, seems to have been infected at some point with a plant paramyxovirus and that the paramyxovirus left one of its genes behind, stuck in the mosquito genome. During this process, I realized that the method I used works with other viruses, too. I tried it with a few random viruses and sure enough, I found some interesting things. You've got a week to give it a try. Let's see ... Read more
Lots of bloggers in the DNA network have been busy these past few days writing about Google's co-founder Sergey Brin, his blog, his wife's company (23andme), and his mutation in the LRRK2 gene. I was a little surprised to see that while other bloggers (here, here, ... Read more
Do mosquitoes get the mumps? Part V. A general method for finding interesting things in GenBank This is the last in a five part series on an unexpected discovery of a paramyxovirus in mosquitoes and a general method for finding other interesting things. In this last part, I discuss a general method for finding novel things in GenBank and how this kind of project could be a good sort of discovery, inquiry-based project for biology, microbiology, or bioinformatics students. I. The back story ... Read more

Privacy     |     Using Molecule World Images    |    Contact

2017 Digital World Biology®  ©Digital World Biology LLC. All rights reserved.