Like many people I know, I suffer from allergies, and sometimes asthma. I take drugs to control the symptoms, but they don't cure the condition. Plus, I know there can be side effects that might not be so pleasant.
This is why I like hearing about sequencing projects that target the VDJ-ome.
I have this fantasy about the things we could do with that information
In a normal immune response (diagrammed below), antibodies on the surface of immature B cells bind to allergens (pollen, dust, whatever). That binding event, plus some help from T cells, ... Read more