phred

Which read(s):

  • 1. contain either a SNP (a single nucleotide polymorphism) or a position where different members of a multi-gene family have a different base?
  • C
  • 2. doesn't have any DNA?
  • B
  • 3. is a PCR product?
  • A, B, and C.  All of three reads were obtained by sequencing PCR products, generated with the same set of primers.
The quality plots that I refer to are ... Read more
Since DNA diagnostics companies seem to be sprouting like mushrooms after the rain, it seemed like a good time to talk about how DNA testing companies decipher meaning from the tests they perform. Last week, I wrote about interpreting DNA sequence traces and the kind of work that a data analyst or bioinformatics technician does in a DNA diagnostics company. As you might imagine, looking at every single DNA sample by eye gets rather tiring. One of the things that informatics companies ( ... Read more

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