This is a multi-part series on antibiotic resistance in bacteria. Eventually, we'll reach the ways in which bacteria develop antibiotic resistance, but before we get there, we'll spend a little more time on antibiotics themselves. What have we learned so far? 1. Antibiotics are natural products, made by bacteria and ...
Two protein structures from an avian influenza virus are shown below. One form of the protein makes influenza virus resistant to Oseltamivir (Tamiflu®) Don't worry, these proteins aren't from H5N1, but they do come from a related influenza virus that also infects birds. One protein structure is from a strain ...
Nick's post on Amantadine resistance in swine flu was so interesting, I had to look at the protein structures myself. I couldn't find any structures with the S31N mutation that Nick discussed, but I did find some structures with the M2 protein and Amantadine. Not only are these structures beautiful ...