Structures of immune cascade complexes from bacteria. These include CRISPR complexes from different bacteria,with guide RNA, target DNA, and the Cas1, Cas2, Cas3, and Cas9 nucleases. This collection of structures can be used to show how bacteria recognize and destroy viral DNA. This system has become an important tool for genome engineering.
iBiology has two nice videos on CRISPR-Cas9
All the structures below can be viewed in Molecule World on the iPad or Molecule World for iPhone.
We have a tutorial here for exploring the CRISPR Cas9 system in Molecule World.
Bio-Link presented a webinar on Genome Engineering with CRISPR Cas9 on Sept 30th.