Thursday, May 29, 2008 - 17:30
I got my copy of "A short guide to the human genome" by Stewart Scherer today from Cold Spring Harbor Laboratory Press (2008, ISBN 978-087969791-4). Usually, I would wait until after I've read a book to write a review, but this book doesn't require that kind of study. As soon I skimmed through it and read some of the questions and answers, I knew this would be the kind of quick reference that I would like to have sitting above my desk. Scherer has compiled a wonderful text that not only answers many of the kinds of questions that I can think to ask about the human genome, but the kinds of questions that I get from my students and other instructors. The whole book in fact consists of questions and answers. Some examples are:
- How common are pseudogenes?
- What is the amino acid composition of a typical protein?
- Which proteins are post-translationally cleaved into multiple hormones and related peptides?
- Which endogenous retroviral genomes are largely intact?
- Which genes and alleles are associated with common genetic diseases?
- How do mitochondrial genomes vary across species?
- Which genes are located in the introns of other genes?